Immunization against rabies with plant-derived antigen
نویسندگان
چکیده
منابع مشابه
Reduced Regiment for Human Pre-exposure Immunization Against Rabies
The main aim of this study was to find a suitable rabies vaccination protocol which would allow usage of lower volumes of vaccine, fewer clinical visits and above all, enough serological effectiveness for high-risk individuals requiring pre-exposure immunization. Human diploid cell rabies vaccine was administered intradermally and intramuscularly in 60 previously unvaccinated volunteers, aged 1...
متن کاملSerological Technique: Immunotherapy (Contd.). Immunization against Rabies
The vaccine.??The Semplc vaccine is used in India and in most other countries. In India, it is a 5 per cent suspension of the brain of a sheep, paralysed after infection with fixed virus of rabies through cisterna puncture. The brain is removed with sterile precautions, ground into 8 per cent suspension with normal saline and phenolized to obtain a concentration of 1 per cent of the antiseptic....
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PURPOSE New alternative bait rabies vaccines applicable to pet dogs and wild animals are needed to eradicate rabies in Korea. In this study, recombinant rabies virus, ERAG3G strain was constructed using reverse genetic system and the safety, efficacy and immunogenicity of the ERAG3G strain was evaluated in mice and dogs. MATERIALS AND METHODS Using the full-length genome mutated amino acid at...
متن کاملInduction of protective immunity against rabies by immunization with rabies virus ribonucleoprotein.
We have studied the ability of rabies virus ribonucleoprotein (RNP) to induce a protective immune response in animals against lethal challenge with rabies and rabies-related lyssa viruses. Liposomes containing either RNP or the glycoprotein (G protein) of a variant virus with multiple alterations in the G antigenic structure conferred no or poor protection, respectively, against lethal intracer...
متن کاملEffective prevention against rabies by intracerebral immunization in mice.
To evaluate the efficacy of intracerebral (IC) immunization, mice were immunized with a rabies vaccine by the subcutaneous (SC), intramuscular (IM) or IC route, and 10-fold the 50% lethal dose of rabies virus was inoculated into the hindleg of the immunized or non-immunized mice. The antibody titer in serum was elevated and boosted by additional immunization via all routes, but highest after th...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1998
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.95.5.2481